蛋白质组学中的质谱（by Lorne Taylor）

仪器资料 · 发表于 2018-2-4 19:44:49

蛋白质组学中的质谱（by Lorne Taylor）
In the past decade and a half, the world of analytical biochemistry has been greatly influenced by
the introduction of new and improved technologies. For example, in the protein science world,
mass spectrometry (MS) has enabled MS-experienced researchers to routinely identify and
sequence proteins at exceedingly low levels (sensitive enough, and better, to analyze silver stained
gel bands, for example). With the advent of the human genome project (and related DNA/RNA
databases), ensembles of technologies (i.e: nanoliter/min HPLC, mass spectrometry and
computerized matching of MS data to DNA sequence) have now presented biological researchers
(with little MS training) the ability to undertake automatic protein analyses on very large sample
sets. Combinations of such technologies have spurred biologists to new ways of thinking, provided
new ways to categorize biology and given rise to new ways to conceptualize living systems at the
molecular level.

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